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Quick Overview

L-Glutamine, the ultimate amino acid, has been shown to:

  • improve mood & mental acuity

  • heighten focus, concentration & memory

  • increase GABA within the body

  • help eliminate brain fog

  • Help acid-alkaline-balance


Ingredients (per Capsule):

500 mg L-Glutamine, gelatin capsule

Contains no fillers, binders or other additives.


L-Glutamine In Your Body

L-Glutamine is 3 - 4 times more concentrated in the blood than any other amino acid and is metabolised in virtually every tissue in the body.  Levels in the order of 100,000 mg are present in the average healthy person. 

L-Glutamine is concentrated in the brain, skeletal muscles, gut lining, lungs, heart, kidneys, & liver.  It is an energy source for the whole body.
It has been observed through blood tests that L-Glutamine levels are almost always sub-optimal in chronically ill patients and those with emotional and cognitive impairments.

L-Glutamine & Brain Function

Glutamine's importance for the brain is born out by its being over ten times more concentrated in the  cerebro-spinal fluid than in the blood.  The brain's major fuel is glucose, but glutamine is a secondary source and can substitute glucose when it is lacking.  This is largely why L-Glutamine is so beneficial for  focus, concentration, memory, intellectual performance, alertness, attentiveness, improving mood, & eliminating brain fog.

The amino acid L-glutamine is also a neurotransmitter.  It sends chemical messages in the brain for proper brain function.  GABA is a calming neurotransmitter, while Glutamate is a stimulating transmitter.  Each drives the brain in one specific direction.  L-Glutamine on the other hand is a modulator of Glutamate and GABA, so the body can use it either to stimulate or calm brain activity.

Your body can also convert L-Glutamine to GABA or Glutamate with the help of the enzyme Glutaminase and adequate co-factors.  Glutamine has also been found to help detoxify the brain of ammonia.

When Glutamine synthesis was blocked in animal studies, convulsions, & Alzheimer’s or senile dementia-type changes were observed in the test subjects' brains.

Acid Alkaline Balance & L-Glutathione

People with a predisposition to acidity, burn up substantial quantities of Glutamine in the kidneys depleting bodily reserves required by the gut, pancreas, brain, liver and every tissue in the body . In acidic conditions there is low Glutamine, low alanine & an increased production of harmful ammonia.
In studies, plasma bicarbonate (which elevates alkaline reserves) & an increase in growth hormone were quickly observed with supplementation of 2000 mg Glutamine daily.

L-Glutamine & Balancing Blood Sugar

L-Glutamine has been shown to help stabilise blood sugar levels, by suppressing insulin when blood sugar is low, thereby preventing a further drop.  Glutamine also stimulates the release of stored glucose reserves and can itself convert to sugar itself to help restore normal sugar levels.

Sugar Cravings, Alcohol Cravings & L-Glutamine

L-Glutamine supplementation has been shown to decrease sugar and alcohol cravings.  A recent study of alcoholics supplementing with 2000mg to 3000mg three times daily between meals, revealed decreased desire to drink, decreased anxiety and improved sleep.

Pancreatic function is key to stable blood sugar.  L-Glutamine supports pancreatic growth & performance.  It increases pancreatic enzyme production and even pancreatic mass, DNA, & protein content, which may contribute substantially to nutritional status.

L-Glutamine and Gut Function

Recent studies have revealed that intestinal toxicity may shut down phase 2 liver detox, which in turn may limit phase 1 liver detoxification.  This is a major finding particularly in the arena of heavy metal detoxification.

Glutamine has been found not only to be a major fuel source for the cells lining the gut wall, but may increase their growth, recovery and absorptive capacity.  Gut wall cells consume up to an incredible 30% of available Glutamine.  A deficiency - which is very common amongst the chronically ill prevents these cells from developing properly and a dysfunction of the associated immune system.

Studies show that Glutamine helps promote healing of impaired gut mucosa , such as with ulcers, ulcerative colitis, & Crohn’s Disease.

L-Glutamine From Foods

The highest L-glutamine food sources are:  pork, poultry, eggs, & dairy proteins, wheat germ, oats & avocados. A healthy diet should deliver between 5,000 and 8,000mg daily. 

Much of the potential Glutamine is delivered as Glutamic Acid.  To create Glutamine from Glutamic Acid in foods, your body needs access to adequate levels of active vitamin B6 , manganese , vitamins and trace minerals (which may for example be obtained from Golden Minerals ).  Without sufficient of these in your diet, you may become Glutamine deficient even though you are consuming sufficient animal or vegetable protein.

Other Benefits of L-Glutathione

  • Important for muscle strength and performance
  • May speed wound heeling
  • Critical for protein metabolism and decomposition of ammonia
  • Important for the synthesis of glutathione a primary anti-oxidant in the liver.
  • Helps to protect the lungs from toxicity.
  • Needed for RNA synthesis
  • Essential for the synthesis of Vitamin B3


1- 2 capsules per day or as recommended by your health-care provider.  We recommend this be taken in conjunction with vitamin B6, manganese  and trace minerals which may ideally be obtained from Golden Minerals.


Those prone to mania need to be careful with high doses of Glutamine for it can trigger mania, as can any antidepressant substance.
Not to be taken with active liver or kidney failure.

Additional Information

SKU 11524
Size 100 Capsules

Due to the nature of our business many expert and professional opinions are expressed on this website.
Where these are not directly related to a particular product such views may not necessarily be in accord with the views of Self Health Enterprises Ltd.

Please note: This information is provided for educational purposes only.
Medical advice is neither implied nor intended.
Please consult a health professional for medical advice.

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